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Reference Data Sets

Below is a description of the characteristics of each of the currently available reference data sets. Each of cases c1 - c5 were first cropped to include the entire ribcage, then sub-sampled in-plane to 256 x 256 voxels. The smaller image volume dimensions are included to ensure that the largest possible range of DIR algorithms is able to be implemented on at least some subset of reference data sets (for example, in some instances computing resources may not be available to determine a DIR solution for a full resolution 512 x 512 x N volume pair). For c1 - c5, the original in-plane voxel dimensions were 0.97 mm x 0.97 mm. Cases 6 - 10 were not subsampled or processed in any way.

The entries in the "# Repeated Measurements" column are formatted as (Nm / Nobs), where Nm is the number of repeated registration measurements for the given case, performed by each of Nobs independent observers. For each case, the "Observer Error" column shows the combined mean repeated registration error for the set of Nobs data sets. The "Landmarked Phases" entries indicate the component phase images for which manually registered landmarks have been identified. T00 represents the maximum inhale phase of the 4DCT, while T50 represents the maximum exhale phase. We will update the available reference data as more cases are added, and as the current sets of landmark correspondences are propagated onto additional component phases for each case. Furthermore, 'BH-CT' indicates image pairs obtained from breath-hold CT.

For the 4DCT data sets, cine loops through representative axial, coronal, and sagittal views are also shown below for each case. In addition, surface renderings of the inhale lung volumes are shown, overlain with displacement vectors (T00 --> T50) for each of the validation landmarks. All surface renderings were generated in the MATLAB (Mathworks, Sunnyvale, CA) environment.

Table 1a. Available Reference Data - 4DCT
Case ID Image Dims Voxel Dims (mm) # Landmarks Avg (SD) Landmark Displacement (mm) # Repeated Measurements Observer Error (SD) (mm) Landmarked Phases
c1 256 x 256 x 94 0.97 x 0.97 x 2.5 1280 4.01 (2.91) 200 / 3 0.85 (1.24) [T00 : T50]
c2 256 x 256 x 112 1.16 x 1.16 x 2.5 1487 4.65 (4.09) 200 / 3 0.70 (0.99) [T00 : T50]
c3 256 x 256 x 104 1.15 x 1.15 x 2.5 1561 6.73 (4.21) 200 / 3 0.77 (1.01) [T00 : T50]
c4 256 x 256 x 99 1.13 x 1.13 x 2.5 1166 9.42 (4.81) 200 / 3 1.13 (1.27) [T00 : T50]
c5 256 x 256 x 106 1.10 x 1.10 x 2.5 1268 7.10 (5.14) 200 / 3 0.92 (1.16) [T00 : T50]
c6 512 x 512 x 128 0.97 x 0.97 x 2.5 419 11.10 (6.98) 150 / 3 0.97 (1.38) [T00 : T50]
c7 512 x 512 x 136 0.97 x 0.97 x 2.5 398 11.59 (7.87) 150 / 3 0.81 (1.32) [T00 : T50]
c8 512 x 512 x 128 0.97 x 0.97 x 2.5 476 15.16 (9.11) 150 / 3 1.03 (2.19) [T00 : T50]
c9 512 x 512 x 128 0.97 x 0.97 x 2.5 342 7.82 (3.99) 150 / 3 0.75 (1.09) [T00 : T50]
c10 512 x 512 x 120 0.97 x 0.97 x 2.5 435 7.63 (6.54) 150 / 3 0.86 (1.45) [T00 : T50]

 

Table 1b. Available Reference Data - COPDgene COMING SOON
Case ID Image Dims Voxel Dims (mm) # Landmarks Avg (SD) Landmark Displacement (mm) # Repeated Measurements Observer Error (SD) (mm) Landmarked Phases
copd1 512 x 512 x 121 0.625 x 0.625 x 2.5 773 25.90 (11.57) 150 / 3 0.65 (0.73) BH-CT pair
copd2 512 x 512 x 102 0.645 x 0.645 x 2.5 618 21.85 (6.58) 150 / 3 1.06 (1.51) BH-CT pair
copd3 512 x 512 x 126 0.652 x 0.652 x 2.5 1172 12.29 (6.39) 150 / 3 0.58 (0.87) BH-CT pair
copd4 512 x 512 x 126 0.590 x 0.590 x 2.5 786 30.90 (13.49) 150 / 3 0.71 (0.96) BH-CT pair
copd5 512 x 512 x 131 0.647 x 0.647 x 2.5 1029 30.90 (14.05) 150 / 3 0.65 (0.87) BH-CT pair

Representative cine loops (4DCT only) and surface renderings are shown below for all available reference data sets listed in Table 1 (click link to view).

Case 1:

Axial Cine Loop
Coronal Cine Loop
Sagittal Cine Loop

c1 displacment renderings

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Case 2:

Axial Cine Loop
Coronal Cine Loop
Sagittal Cine Loop

c2 displacement renderings

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Case 3:

Axial Cine Loop
Coronal Cine Loop
Sagittal Cine Loop

c3 displacement renderings

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Case 4:

Axial Cine Loop
Coronal Cine Loop
Sagittal Cine Loop

c4 displacement renderings

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Case 5:

Axial Cine Loop
Coronal Cine Loop
Sagittal Cine Loop

c5 displacement renderings

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Case 6:

Axial Cine Loop
Coronal Cine Loop
Sagittal Cine Loop

case 6 render

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Case 7:

Axial Cine Loop
Coronal Cine Loop
Sagittal Cine Loop

case7render

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Case 8:

Axial Cine Loop
Coronal Cine Loop
Sagittal Cine Loop

case 8 render

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Case 9:

Axial Cine Loop
Coronal Cine Loop
Sagittal Cine Loop

case 9 - render

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Case 10:

Axial Cine Loop
Coronal Cine Loop
Sagittal Cine Loop

case 10 - render

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Contact Us:

DIR-lab
c/o Richard Castillo
The University of Texas M. D. Anderson Cancer Center
1515 Holcombe Blvd - Unit 56
Houston, TX 77030

E-mail: Inquiries@DIR-lab.com